International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Krishna G Balachandran Nair
Department of Pathology, Government Medical College, Trivandrum, Kerala, IndiaPublications
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Research
Clinicopathological study of vesiculobullous diseases with special emphasis on autoimmune disorders-two year study in a resource setting
Author(s): Sherin Daniel*, Nandakumar G, Krishna G Balachandran Nair and Santha Sadasivan
Objective: To identify the characteristic histopathologic findings and analyse the diagnostic concordance between clinical and histopathological diagnosis of patients with vesiculobullous diseases. Methods: This was a two-year descriptive study conducted in the Department of Pathology where all skin biopsies diagnosed as vesiculobullous diseases were included. A detailed history and relevant clinical examination findings were documented. The specimens were formalin-fixed, paraffin-embedded and stained with haematoxylin and eosin. Direct immunofluorescence was advised for patients where histopathologic features were inconclusive. Results: There were 111 skin biopsy specimens included in the study. Demographic details showed female predominance (65.8%) and the most frequent age group being (40-69) years (29%). Generalised distribution of the lesions over the trunk (53%) associated with .. Read More»
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