Can Hydroxychloroquine Prophylaxis be Useful among Health Care Workers in Prevention of COVID-19?
Author(s): Sacit Icten*, Pinar Ergen, Ozlem Aydin, Hulya Caskurlu, Ayse Canan Ucisik, Gorkem Alper Solakoglu, Onur Incealtin, Kurtulus Aciksari, Ferhat Arslan, Yasemin Cag and Haluk Vahaboglu
Introduction: This study aims to evaluate the pre-exposure and post-exposure efficacy of hydroxychloroquine prophylaxis among Healthcare Workers (HCW) to prevent COVID-19 infection. Materials and Methods: This was a retrospective cohort study. Pre-exposure prophylaxis was given to the HCW in the pre-exposure group according to their willingness. Post-exposure prophylaxis was initiated to HCW after exposure in the hospital or social area within 96 hours. The main outcome was symptomatic or asymptomatic COVID-19 infection confirmed by PCR during the study period for the pre-exposure prophylaxis group and symptomatic or asymptomatic COVID-19 infection confirmed by PCR within 5 to 14 days from exposure for the post-exposure prophylaxis group. An online structured survey was sent to HCW participating in the study. The data were also validated by the available medical records of the hospita.. Read More»