International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Lekha Sreedharan
Clinical Dietetics, Apollo Children’s Hospitals, Chennai, IndiaPublications
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Research
Evaluation of Semi-Elemental Formulae vs. Polymeric Formulae as Exclusive Enteral Nutrition in Active Pediatric Crohn’s Disease in India
Author(s): Lekha Sreedharan*, Dhanasekhar Kesavelu and Anusuya Devi K
Background and aim: Exclusive Enteral Nutrition (EEN) is an evidence-based therapy for pediatric Crohn’s Disease (CD). Various clinical studies are conducted to compare the efficacy of polymeric versus elemental formulae in CD. This is the first Indian prospective observational study comparing the therapeutic efficacy of Polymeric Formulae (PF) vs. Semi-Elemental Formulae (SEF) to maintain clinical remission in Pediatric CD. Method: Children with active CD, who commenced on EEN were enrolled. The cohorts were assessed nutritionally and their disease activity was measured using Pediatric Crohn’s disease activity Index. Data were recorded at baseline and after 8 weeks of post EEN. Result: Out of the 38 children recruited, 20 children were treated with SEF and 18 children with PF. 45% children and 50% children were well-nourished in the SEF and PF group respectively. One chil.. Read More»
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